Celiac Disease Test

  • Enhanced Biomarker screening

  • Physician reviewed results

  • Easy to understand online report

Celiac Test Suite
  • Enhanced Biomarker screening

  • Physician reviewed results

  • Easy to understand online report

The imaware™ mission is to reduce the number of undiagnosed celiac patients.

Celiac Disease is one of the most underdiagnosed diseases in the world[A]


Americans are currently affected by Celiac Disease


of those affected are undiagnosed

Have you experienced any celiac disease symptoms?

You may have celiac disease if you have experienced any of the following symptoms:

• Bloating

• Weight loss

• Cramps

• Digestion issues

In addition, you may have celiac disease if a family member of yours has been diagnosed, as first-degree family members are 15x more likely to have celiac disease as well.[B]

Don’t leave the celiac awareness question unanswered

Choose a quick and easy testing experience

It takes the average American 4 years from recognizing symptoms to be diagnosed with celiac disease. imaware™ provides results back within 5 days to help speed up diagnosis.

Take advantage of early detection

Early detection and adjustment to lifestyle habits are critical to improving quality of life and reducing unnecessary pain and suffering.

imaware Product Presentation

Designed alongside world-class doctors

imaware™ designs and validates each at-home health test alongside world-renowned medical doctors and scientific researchers.

Dr. GuandaliniMedical Director of the University of Chicago Celiac Disease Center.

Dr. SchuppanDiscovered the tTG biomarker for use in the identification of Celiac Disease.

Designed & Validated by Doctors

imaware™ is a simple and precise home-based screening test for celiac disease that should significantly reduce the number of undiagnosed patients over time."
Dr. Stefano GuandaliniMedical Director, University of Chicago Celiac Disease Center

Designed & Validated by Doctors

imaware™ is a simple and precise home-based screening test for celiac disease that should significantly reduce the number of undiagnosed patients over time."
Dr. Stefano GuandaliniMedical Director, University of Chicago Celiac Disease Center

imaware™ At-Home Celiac Disease Test

At-home Collection

imaware™ tests are completed in the comfort of your own home with just a small finger prick. No prescription required.


Complete in under 5 minutes

imaware™ tests use a simple painless process that can be completed in under 5 minutes from the comfort of your own home.

A more accurate analysis

Patented imaware™ technologies create reports for patients that provide high levels of accuracy, reducing the number of unnecessary patient visits to their doctor.[C][D][E][F]


Enhanced biomarker screening

The preferred screening method currently tests for tTG-IgA. imaware™ tests for tTG-IgA along with 3 additional biomarkers to provide a more comprehensive result.[G][H][I][J][K]

Easy to understand online report

Access your results anywhere, any time, and share them easily with your healthcare professional.


Engage your Physician Sooner

We provide you clear next steps and guide you to engage your doctor sooner.

Utilizing the “Screening Gold Standard”

We utilize the highly sensitive and specific Tissue Transglutaminase (tTG) Antibody, or tTG-IgA biomarker for screening the majority of celiac disease patients.

This biomarker has shown to be highly accurate when screening for celiac disease in 98% of the celiac population, and is labeled the “screening gold standard”. Some scenarios may exist where tTG-IgA is negative, and our test also screens for increased tTG-IgG and DGP-IgG biomarker scenarios.

Utilizing tTG-IgA for screening means you can confidently share these results with your doctor knowing they will concur with this common testing standard.

Using an imaware™ collection kit

The imaware™ home collection kit is easy to use, painless, and requires only 5 drops of blood.


Draw 5 drops of blood

Use the pain-free lancet by pressing it against the tip of your finger and press the button


Collect in the microtube

Collect the drops of blood from your finger into a microtube


Secure and return microtube

Secure the microtube, and mailing it back to us with the provided return label.


Check your results online

Your results are available online for review within 5 days

Partners for Celiac Disease Awareness

We're working with our partners to increase awareness of celiac disease home-based testing plus education and community building.

Take the test. Change your life.

Ready to join the thousands of Americans taking control of their health?

Celiac Test Suite

Still have questions about how imaware™ works?

Here are just a few of the things people frequently ask about imaware. If you don’t see your question here, get in touch with us by clicking here.

How do I prepare for my celiac disease test?
You do not need to fast or make any special preparations to complete your celiac disease screening test. We do require patients to be eating small amounts of gluten in order to measure your immune response.
Will this test be accurate if I'm currently eating only gluten-free foods?
Like all blood tests, we test your immune response to the presence of gluten. This requires you to eat the equivalent of 1/2 slice of bread or 2 crackers daily for a period of 8 weeks.
What are celiac disease biomarkers?
A celiac-specific biomarker is a measurable indicator of your body's response or condition to gluten. The two most common celiac biomarkers are tTG and DGP. In patients with celiac disease, these specific biomarkers are found to be elevated.
What makes the imaware™ celiac disease test unique?
imaware™ is a comprehensive test for celiac disease that utilizes the prevalence of family history, diabetes, and other relevant conditions in our report. Our test also measures multiple celiac disease biomarkers and combines the results together to provide more accurate insights of your celiac condition.
Is the imaware™ celiac disease test as accurate as a DNA test for celiac disease?
imaware™ celiac disease test is more accurate, as it tests your blood for presence of celiac disease biomarkers. DNA kits test for the genetic markers that may indicate a predisposition for celiac disease.
What is the difference between celiac disease and non-celiac gluten sensitivity?
Celiac disease is an auto-immune disorder that occurs in response to the ingestion of gluten. Non-celiac gluten sensitivity is the least understood reaction to gluten, and can be investigated after celiac disease is ruled out.
Are there any special return shipping instructions?
No, simply drop-off the package in the provided shipping bag at any USPS mailbox or store location at any time.
View the notes of scientific references for claims made on this page
Rubio-Tapia A, Ludvigsson JF, Brantner TL, et al.
The prevalence of celiac disease in the United States.
Am J Gastroenterol 2012; 107(10):1538-44
Wessels MMS, de Rooij N, Roovers L, Verhage J, de Vries W, Mearin ML.
Towards an individual screening strategy for first-degree relatives of celiac patients. Eur J Pediatr. 2018.
Akobeng AK.
Understanding diagnostic tests 2: likelihood ratios, pre- and post-test probabilities and their use in clinical practice.
Acta Pædiatrica 2006; 96:487–91
Sonis J.
How to Use and Interpret Interval Likelihood Ratios.
Fam Med 1999; 31(5):432-7
Parikh R, Parikh S, Arun E, et al.
Likelihood ratios: Clinical application in day-to-day practice.
Indian J Ophthalmol. 2009; 57(3): 217–221
Vermeersch P, Richter T, Hauer AC, et al.
Use of likelihood ratios improves clinical interpretation of IgG and IgA anti-DGP antibody testing for celiac disease in adults and children.
Clinical Biochemistry 2011; 44:248–250
Giersiepen K(1), Lelgemann M, Stuhldreher N, Ronfani L, Husby S, Koletzko S,Korponay-Szabó IR; ESPGHAN Working Group on Coeliac Disease Diagnosis.
Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report.
J Pediatr Gastroenterol Nutr. 2012 Feb;54(2):229-41. doi: 10.1097/MPG.0b013e318216f2e5.
Matthijs Oyaert, Pieter Vermeersch, Gert De Hertogh, Martin Hiele, Nathalie Vandeputte, Ilse Hoffman and Xavier Bossuyt*
Combining antibody tests and taking into account antibody levels improves serologic diagnosis of celiac disease
DOI 10.1515/cclm-2013-1099 Received December 21, 2013; accepted January 9, 2015; previously published online February 19, 2015
Ingrid Dahlboma, Britt-Inger Nyberga, Lillemor Berntsona and Tony Hansson
Simultaneous detection of IgA and IgG antibodies against tissue transglutaminase: The preferred pre-biopsy test in childhood celiac disease Departments of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden; Departments of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, 26 February 2016
Pieter Vermeersch,* Karel Geboes,‡ Godelieve Mariën,* Ilse Hoffman,§ Martin Hiele,︎ and Xavier Bossuyt
Defining Thresholds of Antibody Levels Improves Diagnosis of Celiac Disease
Lakos G, Norman GL, Mahler M, et al.
Analytical and Clinical Comparison of Two Fully Automated Immunoassay Systems for the Diagnosis of Celiac Disease.
Journal of Immunology Research, vol. 2014, Article ID 371263, 9 pages, 2014.

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